Microvolt T-Wave Alternans in Patients with a Biventricular Implantable Defibrillator

Authors

  • Therese Fuchs Assaf Harofeh Medical Center
  • Marina Leitman Assaf Harofeh Medical Center
  • Amram Torjman College of Management, Rishon- Le-Zion

DOI:

https://doi.org/10.2015/hc.v6i3.380

Keywords:

T wave alternans, heart failure, cardiac resynchronization.

Abstract

Background/Aim: Microvolt T-wave alternans (MTWA) has been found to be associated with cardiac electrical instability. The aim of this study was to investigate the effects of biventricular pacing on MTWA in comparison with other pacing modalities.

Methods: The study group consisted of 50 patients with dilated or ischemic cardiomyopathy with a cardiac resynchronization therapy device. MTWA was measured during several pacing modalities.

Results: Overall, 181 MTWA studies were performed in 50 patients. Seventy-nine studies (44%) were negative, 81(45%) were positive and 21 (12%) were indeterminate. With right atrial (RA) pacing, 45% of the MTWA tests were negative. With right ventricular (RV) pacing, 30 % were negative, with left ventricular (LV) pacing 44 % were negative and with biventricular pacing 52% of the tests were negative (P=0.15). The results of TWA testing were concordant between RA pacing and biventricular pacing (K=0.46, P=0.007).

Conclusion: MTWA during biventricular pacing correlates with MTWA during atrial pacing and left ventricular pacing.

Author Biographies

Therese Fuchs, Assaf Harofeh Medical Center

Cardiology department

Director of EP

Marina Leitman, Assaf Harofeh Medical Center

Department of Cardiology

Downloads

Additional Files

Published

2011-03-21

Issue

Vol. 6 No. 3 (2011)

Section

ORIGINAL ARTICLES

License

Authors who publish with this journal agree to the following terms:

a. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.

b. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.

c. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).