Acute Kidney Injury in Patients with COVID – 19 Infection: Α Tertiary Referral Hospital Experience

Authors

  • Dr. Christina- Danai Skondra Department of Nephrology, Evagellismos General Hospital, Ipsilantou 45-47, 10676, Athens, Greece
  • Dimitra Kozikopoulou
  • Theodora Oikonomaki
  • Glikeria Tsouka
  • Myrto Giannopoulou
  • Eleni Magira
  • Elias Siempos
  • Stylianos Kokkoris
  • Spyridon Zakynthinos
  • Christalleni Christodoulidou

Abstract

The emersion of the new coronavirus SARS COV 2 (Severe Acute Respiratory Syndrome
Coronavirus 2) was rapidly characterized as a pandemic by WHO. The major
manifestation of the virus is respiratory distress; however, the involvement of other organs
should not be overlooked. The kidney is one of the most important target organs
of the specific virus with acute kidney injury (AKI) described in 5-36% of COVID
positive patients and an average 25% within the severely ill.
Purp ose: The purpose of this study was to consider the incidence of AKI in patients
with COVID 19 in our cohort and to better understand risk factors associated with
AKI. Further, we wanted to investigate the impact of AKI on survival and in hospital
mortality.
Methods: Patients admitted to Evagelismos General Hospital with confirmed COVID-
19 infection from 11th March until 22th May were investigated. Patients 18 years
old as well as transplanted patients were excluded from this study. AKI was defined
according to the AKI criteria.
Results : From 99 patients with COVID-19 infection, AKI occurred in 41 (41.4%).
A total of 44 patients (44.4%) were admitted to Intensive Care Unit (ICU) and 31 of
them (70.5%) developed AKI. Of the 44 patients with AKI, 16 (39%) required renal
replacement therapy. Hospital mortality, in total, was 16.2% (37% among patients
with AKI versus 0.02% among those without AKI, p=0.000).
Conclusion: AKI was common among patients hospitalized with COVID 19. AKI
was associated with older age, clinical severity and existing CKD.

Downloads

Published

2021-09-02

Issue

Vol. 16 No. 1 (2021): Hospital Chronicles (Nosokomeiaka Chronika)

Section

ORIGINAL ARTICLES

License

Authors who publish with this journal agree to the following terms:

a. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.

b. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.

c. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).