Challenges and Caveats for Stents of New Technology: Which Stent is Better? What are the Results in High-risk Patients?
Keywords:coronary angioplasty, coronary stenting
Coronary stenting has revolutionized percutaneous coronary revascularization. Two landmark studies published in 1994, Benestent and STRESS, demonstrated the significantly superior outcomes of intracoronary stenting versus balloon angioplasty. However, the success of bare-metal stents was limited by the occurrence of neointimal hyperplasia (NIH) leading to in-stent restenosis (ISR). The problem of neointimal hyperplasia, as measured by late loss, represented a significant hurdle, limiting the long-term patency of stents in many patient populations. The solution to the problem of ISR (the Achilles heel of the stent) was given by the evolution of new stent platforms coated with polymers eluting anti-proliferative drugs, drug eluting stents-DES... (excerpt)
LicenseAuthors who publish with this journal agree to the following terms:
a. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
b. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
c. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).