European Lung Cancer Working Party Clinical Practice Guidelines Non-small Cell Lung Cancer: II. Unresectable Non-metastatic Stages

Authors

  • Costas G. Alexopoulos
  • Thiery Berghmans
  • Marie-Claude Merchier
  • Benoit Colinet
  • Didier Dequanter
  • Anna Efremidis
  • Marie-Chantal Florin
  • Vicente Giner
  • Stefane Jouveshom
  • George Koumakis
  • Jean-Jacques Lafitte
  • Jacques Lecomte
  • Jean Lemaitre
  • Ingrid Louviaux
  • Celine Mascaux
  • Anna-Pascale Meert
  • Vincent Ninane
  • Michel Richez
  • Jean-Paul Sculier
  • Bruno Stach
  • Michael M. Vaslamatzis
  • Patricia Wackenier

DOI:

https://doi.org/10.2015/hc.v1i2.14

Keywords:

non-small cell lung cancer, radiochemotherapy, unresectable, chest irradiation, non-metastatic stages

Abstract

The present guidelines on the management of unresectable non-metastatic non-small cell lung cancer (NSCLC) were formulated by the ELCWP in October 2005. They are designed to answer the following eight questions: 1) Is chest irradiation curative for NSCLC? 2) What are the contra-indications (anatomical or functional) to chest irradiation? 3) Does the addition of chemotherapy add an advantage to radiotherapy? 4) Does the addition of radiotherapy add an advantage to chemotherapy? 5) Is irradiation as effective as surgery for marginally resectable stage III? 6) How to best combine chemotherapy with radiotherapy: sequentially, concomitantly, as consolidation, as induction, as radiosensitiser? 7) In case of too advanced locoregional disease, is there a role for consolidation (salvage) local treatment (surgery or radiotherapy) after induction chemotherapy? 8) In 2005, what are the technical characteristics of an adequate radiotherapy?

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Issue

Vol. 1 No. 2 (2006)

Section

Special Topic

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