New Oral Antithrombotic Drugs

Authors

  • Vana Christopoulou Cokkinou

DOI:

https://doi.org/10.2015/hc.v1i2.10

Keywords:

Oral antithrombotics, triclopidine, clopidogrel, ximelagatran, thromboembolic disease

Abstract

New oral antithrombotic drugs are currently used for several indications, but mostly for the long-term treatment or prevention of thromboembolic disease in situations such as high-risk orthopedic surgery, deep vein thrombosis and myocardial infarction. They are also used in atrial fibrillation for the prevention of stroke. This family of drugs includes anti-platelet agents, eg. ticlopidine and clopidogrel, antithrombin agents, eg. ximelagatran and several others with various mechanisms of action. Oral intake has to fulfill certain conditions regarding absorption, efficacy and safety.

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